If you shave a guinea pig, and then
sandpaper the animal's skin until it is pink, but doesn't
bleed, it can be shown that the animal has become as sensitive
to poison-oak as people are.
Skin Care
Harmful substances, like
poison-oak sap, are kept out of our bodies by the stratum
corneum, a layer of overlapping coin-shaped cells, 1 to 150
cells thick. The tiny cracks between these cells are often
filled with skin oil (sebum). Many observations about the
effects of poison-oak relate to the thickness of or amount of
oil in this layer.
For example, people with open and
healing wounds should bandage those areas prior to exposure.
Also, bathing or vigorously washing your hands just before
exposure is bad; it takes 4 hours to replace your sebum.
Most modern cosmetics contain an
excipient a spreading agent. Therefore, they make an
additional layer for poison-oak to penetrate, which may
provide enough protection to keep you rash free. An example is
Neutrogena Sensitive Skin Sunblock Lotion (SPF 30). It can be
smeared on your face, including eyelids; hands, including
under your jewelry; and genitals.
If you are mildly sensitive, you
can also experiment with cooking oils, e.g. corn, canola,
peanut and sesame seed oils as liquids or sprays; clays of all
kinds, including mud from puddles; the saps of other plants,
for example mugwort; collodion, available at specialty glass
shops it prevents people who handle glass a lot from getting
splinters; mechanics waterless grease remover; or whatever
else youd like to try.
Clothing
We
have rattlesnakes, ticks, brush and rocky soils to contend
with, in addition to poison-oak. So we dress to deal with all
five.
The
topic of clothing is a big one. For example, bare feet are
sometimes fine on a sandy beach. However, this section only
discusses clothing for trail work.
For
routine trail work, sneakers; ankle-height socks; long pants;
long-sleeved shirt; gloves and a hat are helpful. Many of us
wear boots instead of sneakers. Some of us also tape our pant
cuffs to keep the ticks off our legs; one-inch-wide painters
masking tape works well for this.
For
crashing around in the brush off trail we wear gaiters to keep
the duff out of our boots.
For
operators of power trimmers a mist is generated that drifts
through wire mesh face guards and wets our faces. We are
trying Stihl concrete cutters hard hats; they have a
polycarbonate face shield, integral ear muffs, and for a few
cents extra can be equipped with a neck drape. Our equipment
operators are also familiar with picking sleeves and gaiters.
We
sometimes prefer to pull out poison-oak by its roots. For this
job a good pair of glove is essential (see Gloves below). A
designated hot pair of hand clippers, picking sleeves, a
mesh face mask, and a hooded shirt or parka are also helpful.
Finally, to keep your family safe after your adventures wash
your own clothes. Only you know what you got into, and how
hot your duds are. This goes for dry cleaning, too; if
theres any question, put the items in a bag, and instruct the
staff to put them in a machine without touching them.
My Gloves
I am moderately sensitive, like
60% of people. Therefore, I offer my routines for limiting
exposure to poison-oak as a starting point for others.
Leather gloves are easily
penetrated by urushiols. They make my hands itch the second
time I use them to hold and pull poison-oak.
I fell in love with neoprene
gauntlet gloves early in my work with poison-oak. Heres my
first pair, just before they got thrown away:

I always wore cotton liners inside of them. I'd put the liners
on, and then pull the gauntlets on by the cuffs. Removing them
I'd pull one gauntlet off, keeping the liner on, and then pull
the other gauntlet off by the fingers. I used them two years
before they became too hot to handle.

Here are the cotton liners. Eventually I felt safe tearing
poison-oak out by its roots with this combination!
Later on I tried using neoprene gloves by themselves, which
gave me greater dexterity and was cooler. However, I found
that California Blackberry thorns pierced them, transmitting
just enough poison-oak sap to make my hands itch. So, for pulling poison-oak I'm using the combination; when cutting poison-oak I wear just the gauntlet gloves.
Handling contaminated tools I get enough protection wearing
just the liners. When my hands begin to itch I launder them. I
do this several times before I throw the liners away.